
Psychiatric News December 3, 2004
Volume 39 Number 23
© 2004 American Psychiatric Association
p. 22
Depressed Patients Do Better When They Get RESPECT
Mark Moran
Physicians using a manualized depression-treatment program were more
thorough in evaluating suicide risk, more likely to hand patients educational
material about depression, and more apt to promote patient
self-management.
A manualized program for treating depression in primary care settings that
emphasizes collaboration between psychiatrists and primary care
physiciansas well as telephone case managementappears to offer
significant improvement in patient outcome over standard care.
In a randomized clinical trial involving three large medical group
practices, two health plans, and more than 400 patients, the manualized
program, called "Re-Engineering Systems for the Primary Care Treatment
of Depression" (RESPECT-Depression), was found to significantly improve
response to treatment, rates of remission, and satisfaction with care.
A report on the trial appears in the September British Medical Journal
(BMJ).
Developed by the MacArthur Initiative on Depression and Primary Care,
RESPECT-Depression integrates work by primary care clinicians who manage
patients, centralized care managers who provide telephone support, and
psychiatrists who supervise the care managers and offer suggestions to
clinicians about treatment and management.
At each practice, clinicians and staff are trained using materials
developed by RESPECT-Depression researchers and customized to each setting by
the organizations.
The MacArthur Initiative is making the RESPECT-Depression materials
available at no cost to medical practices that want to adopt it. Those
materials can be downloaded from the Web at
<www.depression-primarycare.org/clinicians/re_engineering/>.
The essential components include training primary care clinicians in the
use of the RESPECT-Depression materials, telephone care management, and closer
relationships between mental health and primary care clinicians, said Allen
Dietrich, M.D., a professor of community and family medicine at Dartmouth
Medical School and co-chair of the MacArthur Initiative.
"Professionals work together through these three components and
provide more systematic patient education, promotion of patient
self-management, and monitoring of suicide risk. Especially important is
supporting modification of the management plan if the patient's symptoms are
not improving."
Follow-up Much More Likely
In the study, 405 patients with depression were randomly assigned to
treatment using the RESPECT-Depression model or standard care. At six months,
60 percent of 177 patients receiving the intervention had responded to
treatment compared with 47 percent of 146 patients in usual-care practices. At
six months, 37 percent of the intervention patients showed remission compared
with 27 percent of the usual-care patients.
Ninety percent of the intervention patients rated their depression care as
good or excellent at six months compared with 75 percent of usual-care
patients.
The organizations participating in the clinical trial were Intermountain
Health Care in Salt Lake City, Colorado Access in Denver, Highmark Blue Cross
Blue Shield in Pittsburgh, and ProHealth Physicians Group in Bloomfield, Conn.
The evaluation center was led by Herbert C. Schulberg, Ph.D., and was based at
Cornell University.
Dietrich said physicians using the intervention were found by independent
evaluators to be more thorough about evaluating suicide risk, more likely to
hand patients educational material about depression, and more likely to
promote self-management on behalf of the patient.
"It's also true that the RESPECT patients were much more likely to
get a series of follow-up contacts from the clinician," Dietrich said.
"They had both more follow-up visits over the three months following the
index visitfollowing the first visit. And they were also much, much
more likely to get a telephone support call."
Treating Returning Soldiers
The military is also interested in adopting the model for treatment of
soldiers returning from overseas.
In a teleconference press briefing about the BMJ report, Charles
C. Engel, M.D., director of the Defense Department's Deployment Health
Clinical Center at Walter Reed Army Medical Center in Washington, D.C., said
the center is working with the RESPECT-Depression team to develop a modified
model of the approach that will help meet the post-war primary care needs of
returning soldiers and their families.
"The RESPECT model could improve early access to needed services,
improve the effectiveness of those services, and reduce stigma by locating the
care in a primary care setting," said Engel.
APA's Darrel Regier, M.D., M.P.H., who also participated in the
teleconference, called RESPECT an "excellent" model that can be
integrated into similar programs for other chronic diseases at the primary
care setting, so that it would not require additional staffing beyond what is
already available.
Regier is head of APA's Office of Research and the American Psychiatric
Institute for Research and Education.
"I think a major problem is probably disseminating it to the smaller
office practices that don't have additional staff available and that don't
already have a preexisting infrastructure of the type that the five
organizations had," Regier said. "But if, in fact, this model can
be demonstrated to be sustained, I think it will be a very nice
contribution."
Regier added that the RESPECT model supports the close monitoring of
antidepressant medication useespecially around suicidal ideation.
"If physicians were using this kind of instrument on a routine basis,
they would be able to address the safety issues that have been raised,"
Regier said.
The report, "Re-engineering Systems for the Treatment of
Depression in Primary Care: Cluster Randomised Controlled Trial," is
posted online at
<www.depression-primarycare.org/images/pdf/bmj.pdf>.
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