Psychiatric News July 4, 2003
Volume 38 Number 13
© 2003 American Psychiatric Association
p. 19
Comparing PANSS, BPRS Results
Brown
Two scales for measuring symptom reduction of schizophrenia patients are commonly used in clinical trials, making comparisons of data across studies a challenge at best. - The Brief Psychiatric Rating Scale (BPRS) is a 16-item scale with nine general symptom items, five positive-symptom items, and two negative-symptom items. Completed by the physician, each item is scored on a seven-point severity scale (the higher the number, the more severe the symptom), resulting in a range of possible scores from 16 to 112. The average patient with schizophrenia entering a clinical trial typically scores 33.
- The Positive and Negative Syndrome Scale (PANSS) is a 30-item scale with 16 general psychopathology symptom items, seven positive-symptom items, and seven negativesymptom items. Also completed by the physician, each item is scored on the same sevenpoint severity scale as the PANSS, resulting in a range of possible scores from 30 to 210. The positive- and negative-symptom item groups are often reported separately, with a possible range of 7 to 49. A patient with schizophrenia entering a clinical trial typically scores 91.
Source:
Geddes J et al; BMJ 2000; 321:1371-76.[Abstract/Free Full Text]
Related Article:
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New Studies Raise Questions About Antipsychotic Efficacy
- Jim Rosack
Psychiatr News 2003 38: 18-19.
[Full Text]
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